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Conclusions: Even with limited availability of advanced imaging extending time windows for reperfusion therapies resulted in an 11,6% increase in thrombolysis and a 42% increase in thrombectomy with similar clinical outcomes in early and late-treated patients at the price of increased burden of clinical and imaging screening
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Efflux CMTs In addition to influx systems of CMTs at the BBB, brain capillary microvasculature embraces some key transport machineries that act as major hindrance against the entry of a number of different therapeutic drugs into the brain parenchyma – a function known as the efflux pumps of BBB
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