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Signs your medication has gone bad Discard the vial immediately if you notice any of the following: cloudiness or haziness in the solution, visible particles or floaters, color changes (most GLP-1 solutions should be clear and colorless), unusual smell when you remove the cap, or if the solution has been past its labeled discard-by date

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When supplements are used as part of a comprehensive treatment plan (with phototherapy or topical treatments), initial visible repigmentation often begins around 3 to 6 months