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Key Research Findings Increased Energy Expenditure: Enhances cellular metabolism by inhibiting NNMT, leading to higher NAD+ levels and increased thermogenic activity
Biochemical Research
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Patients with high NNMT levels tend to have poor prognostic parameters and overall survival (OS) and disease-free survival (DFS) ( NNMT gene silence can increase radiosensitivity and chemosensitivity in GBM and CMM, which contributes to combating drug resistance and optimizing combination therapy
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