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Because of the unique reactivity of α,β-unsaturated aldehydes generated during lipid peroxidation, including the most frequently evaluated 4-HNE in plasma, an increased concentration of 4-HNE–modified proteins in the plasma of patients with neuroborreliosis has also been demonstrated, which indicates a different, not directly oxidative, but resulting from the modification of the structure and, consequently, the function of proteins (Moniuszko-Malinowska et al., 2016)
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