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Sources: [1] Nature New Biology · 1973 · [3] Journal of Biomaterials Science, Polymer Edition · 2008 · [5] International Journal of Molecular Sciences · 2018 03 What researchers have studied Most published work comes from cell and animal models and from formulation studies: Tissue remodeling and collagen-related signaling
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Consequences of this include oxidative damage to DNA, proteins and cell membrane lipids, and altered cellular signal transductions as observed in many disorders such as diabetes, cardiovascular, autoimmune and chronic kidney diseases [5]
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