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Furthermore, it is possible that somatostatin directly inhibits glucagon secretion by binding to its receptor in the alpha cell, since GLP- 1 stimulates islet somatostatin secretion directly through the canonical GLP- 1 receptor, expressed on delta cells [71]
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Π’Π΅ ΡΠ° ΠΏΡΠ±Π»ΠΈΠΊΡΠ²Π°Π»ΠΈ ΡΠ»Π΅Π΄Π½ΠΈΡΠ΅ ΠΏΡΠΎΡΡΠ²Π°Π½ΠΈΡ: ΠΠ·ΡΠ»Π΅Π΄Π²Π°Π½Π΅ in vitro Π²ΡΡΡ Ρ ΡΡΡΠ·Π°Π½ΠΈ ΡΡΡ ΠΎΠΆΠΈΠ»ΠΈΡ ΠΏΡΠ΅Π΄ΠΏΠΎΠ»Π°Π³Π°, ΡΠ΅ BPC-157 ΠΌΠΎΠΆΠ΅ Π΄Π° ΡΡΠΈΠΌΡΠ»ΠΈΡΠ° ΠΌΠΈΠ³ΡΠ°ΡΠΈΡΡΠ° ΠΈ ΡΠ°Π·ΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΠ΅ΡΠΎ Π½Π° ΡΠΈΠ±ΡΠΎΠ±Π»Π°ΡΡΠΈ (ΠΊΠ»Π΅ΡΠΊΠΈ ΠΊΠΎΠΈΡΠΎ ΠΏΡΠΎΠ΄ΡΡΠΈΡΠ°Ρ ΠΊΠΎΠ»Π°Π³Π΅Π½) ΠΊΡΠΌ ΠΌΡΡΡΠΎΡΠΎ Π½Π° Π½Π°ΡΠ°Π½Π΅Π½Π°ΡΠ° ΡΡΠΊΠ°Π½ [19]
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