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NMR experiments were performed using 15 N-labeled Ξ±Syn WT in the absence and presence of either unlabeled Ξ±Syn WT or Ξ±Syn 1β103 at a 1:1 molar ratio in PBS containing 10% (v/v) DβO
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This significantly reduces cystine uptake, leading to osteoclast apoptosis and ultimately accelerating the development of osteoporosis (41)
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