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It does not rescue a vial where a non-sterile needle was used or where a particulate was introduced
blood cell formation
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It is currently postulated that IDO1, IDO2, and TDO activity can cause near total depletion of cellular tryptophan, which in turn triggers an accumulation of uncharged tRNAs and consequently activates the GCN5 kinase pathway and causes T cell dysfunction [75]
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