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Increased abdominal pressure was maintained (measurement interval of 1 s) at 25 mmHg for 60 min, at 30 mm for 30 min, and at 40 mm Hg for 30 min until the decompression (laparotomy and calvariectomy) and then followed by reperfusion for 60 min (25 mmHg), 30 min (30 mm Hg), or 30 min (40 mm Hg) until sacrifice
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[7] In summary, while Tri-Mix’s local mechanism means drug-drug interactions are limited, concurrent use of other ED treatments or vasodilators can amplify systemic effects
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