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In the organ of Corti, a small group of supporting cells express G-protein-coupled receptor (Lgr5), and are believed to possess progenitor-like activities (Shi et al., 2013)
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The researchers monitored the effect of FOXO4-DRI on a group of aged laboratory mice, noting a significant decrease in the number of senescent Leydig cells and a parallel increase in the concentration of testosterone in the blood plasma
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