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Friedreich’s ataxia (MIM# 229300) Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disorder caused primarily by a homozygous GAA repeat expansion within intron 1 of the frataxin ( FXN ) gene, located on chromosome 9q21.1 [164]
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5 Novel revelations regarding cell death mechanisms in discrete nuclei affected in PD, notably within critical centers like the respiratory system Current understanding about the role of cell death in Parkinson’s disease is due to neurodegeneration in midbrain, notably within the SN
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