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Proliferation, survival, migration, tubulogenesis and in vivo neovascularisation of HUVEC (human umbilical vein endothelial cells) was increased significantly more with the HGF-containing conditioned medium of MDR HCC cells, compared to the conditioned medium of the isogenic parental chemosensitive cells, which contained no HGF [34]
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The development of these systems could facilitate the use of promising pharmaceutical compounds that have traditionally been limited by their poor pharmacokinetic profile
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