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While PPIs are effective in providing symptom relief over time in both erosive and non-erosive disease, as shown in studies comparing PPIs with P-CABs 135,136 this combination therapy may achieve in 2 weeks the same symptom relief that PPIs typically provide in 4 weeks
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Another priority is to investigate the tissue-specific roles of NNMT, particularly in the vascular endothelium, cardiomyocytes, and metabolically active organs such as the liver and adipose tissue
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