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Reported with CJC-1295 (Teichman 2006 and related): Injection site reactions (redness, swelling, pain at the subcutaneous injection site — the most commonly reported adverse event in the Teichman trial) Transient flushing and headache (reported in the acute post-injection period) Water retention or peripheral edema (a recognized GH class effect associated with sodium retention) Potential for IGF-1 elevation above the age-adjusted reference range at higher doses (requires monitoring) Reported with ipamorelin (Raun 1998, Gobburu 1999, Beck 2014): Injection site discomfort Transient flushing and headache in the acute post-injection window Increased appetite (a ghrelin-receptor class effect
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