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Immunologic stimulation of mast cells leads to the reversible exposure of phosphatidylserine in the absence of apoptosis

NPD2025

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If GSH is severely depleted by the toxic metabolite of acetaminophen, NAPQI (Figure 3b), and/or there is inadequate glycine to produce GSH due to illness or nutritional deficiency, there is a lack of negative feedback of GSH on γ-glutamylsynthetase