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Atractylodes macrocephala exhibits anti-hyperuricemic and anti-inflammatory properties in animal models, reducing IL-1ฮฒ and TNF-ฮฑ levels while activating AMPK/SIRT1 signaling and suppressing NF-ฮบB-mediated macrophage polarization toward pro-inflammatory phenotypes (Qian et al., 2023)
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