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Impaired individuals exhibit hypomethylation of CpG sites in the CCL11 promoter region, which are then hypermethylated upon supplementation with B12 In impaired individuals, three CpG sites exhibited hypomethylation when compared to the non-impaired group
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Therefore, a disulfide derivative that does not need the transporter is a method by which thiamine can be introduced to the cell when the transporter is missing
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